Journal of Veterinary Research (Jan 2021)

Comparative expression analysis of inflammatory and immune-related genes in cattle during acute infection with foot-and-mouth disease virus in Egypt

  • El Nahas Abeer F.,
  • Abd El Naby Walaa S.H.,
  • Khatab Shymaa A.,
  • Fergany Al-Zahraa A.,
  • Rashed Rashed R.

DOI
https://doi.org/10.2478/jvetres-2021-0005
Journal volume & issue
Vol. 65, no. 1
pp. 39 – 44

Abstract

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Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of the present study was, for the host factors associated with different FMDV infections in cattle during the acute phase, to compare these factors’ influence on the expression of the IL-10, TLR-2, TNF-α, CXCL10, CD48, NFATC4 and IFNG inflammatory and immune-related genes.

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