Auxin-induced signaling protein nanoclustering contributes to cell polarity formation

Xue Pan; Linjing Fang; Jianfeng Liu; Betul Senay-Aras; Wenwei Lin; Shuan Zheng; Tong Zhang; Jingzhe Guo; Uri Manor; Jaimie Van Norman; Weitao Chen; Zhenbiao Yang

doi:10.1038/s41467-020-17602-w

Nature Communications (Aug 2020)

Auxin-induced signaling protein nanoclustering contributes to cell polarity formation

Xue Pan,
Linjing Fang,
Jianfeng Liu,
Betul Senay-Aras,
Wenwei Lin,
Shuan Zheng,
Tong Zhang,
Jingzhe Guo,
Uri Manor,
Jaimie Van Norman,
Weitao Chen,
Zhenbiao Yang

Affiliations

Xue Pan: FAFU-UCR Joint Center for Horticultural Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University
Linjing Fang: Waitt Advanced Biophotonics Center, The Salk Institute for Biological Studies
Jianfeng Liu: Center for Plant Cell Biology, Institute of Integrative Genome Biology, and Department of Botany and Plant Sciences, University of California
Betul Senay-Aras: Department of Mathematics, University of California
Wenwei Lin: FAFU-UCR Joint Center for Horticultural Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University
Shuan Zheng: FAFU-UCR Joint Center for Horticultural Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University
Tong Zhang: Waitt Advanced Biophotonics Center, The Salk Institute for Biological Studies
Jingzhe Guo: Center for Plant Cell Biology, Institute of Integrative Genome Biology, and Department of Botany and Plant Sciences, University of California
Uri Manor: Waitt Advanced Biophotonics Center, The Salk Institute for Biological Studies
Jaimie Van Norman: Center for Plant Cell Biology, Institute of Integrative Genome Biology, and Department of Botany and Plant Sciences, University of California
Weitao Chen: Department of Mathematics, University of California
Zhenbiao Yang: Center for Plant Cell Biology, Institute of Integrative Genome Biology, and Department of Botany and Plant Sciences, University of California

DOI: https://doi.org/10.1038/s41467-020-17602-w
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 14

Abstract

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The significance of protein nanoclustering in cell polarization is unclear. Here Pan et al. show that auxin-induced TMK1/sterol nanoclustering as well as microtubule-based positive feedback regulation of the TMK1/sterol nanoclusters is critical for cell polarity formation in Arabidopsis.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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