Biomedicine & Pharmacotherapy (Sep 2020)

Bone metabolism regulation: Implications for the treatment of bone diseases

  • Danqi Yao,
  • Lianfang Huang,
  • Jianhao Ke,
  • Ming Zhang,
  • Qin Xiao,
  • Xiao Zhu

Journal volume & issue
Vol. 129
p. 110494

Abstract

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Bone cells in the human body are continuously engaged in cellular metabolism, including the interaction between bone cells, the interaction between the erythropoietic cells of the bone marrow and stromal cells, for the remodeling and reconstruction of bone. Osteoclasts and osteoblasts play an important role in bone metabolism. Diseases occur when bone metabolism is abnormal, but little is known about the signaling pathways that affect bone metabolism. The study of these signaling pathways will help us to use the relevant techniques to intervene, so as to improve the condition. The study of these signaling pathways will help us to use the relevant techniques to intervene, so as to improve the condition. I believe they will shine in the diagnosis and treatment of future clinical bone diseases.

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