A Study of helicobacter pylori presence in patients with gastrointestinal disorder

Abstract

Helicobacter pylori infection causes gastric and duodenal ulcer. However recurrence of"ninfection after eradication would suggest the existence of other reinfecting sources in the gastrointestinal"ntract (Gl). The aim of this study was to assess the existence ofhelicobacter pylori in dental plaques of"npatients harboring Helicobacter pylori in their GI tract. Antral biopsies were taken from 40 patients with"nGl problems and cultured. Samples were also taken from dental plaques of patients with positive"nHelicobacter pylori culture under microaerophilic conditions and evaluated by polymerase chain reaction"n(PCR) reamplification. The mean age of patients was 40 years; 24 (60%) male and 16 (40%) female. The"nresults obtained from dental plaque cultures, which analysed by PCR were all negative, however 7"n(17.5%) cases were found positive by PCR reamplification. The results showed that Helicobacter pylori"ncould exist in dental plaque and PCR reamplification could be used for its detection as a more sensitive"ntechnique. More research should be conducted to examine any relation between the existence of"nHelicobacter pylori in dental plaques and recurrent GI disorders.

Keywords

• Helicobater pylori