BMC Nephrology (Jul 2020)

An unusual cause of metabolic alkalosis: hiding in plain sight

  • Carmen Elena Cervantes,
  • Steven Menez,
  • Bernard G. Jaar,
  • Mohamad Hanouneh

DOI
https://doi.org/10.1186/s12882-020-01967-7
Journal volume & issue
Vol. 21, no. 1
pp. 1 – 4

Abstract

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Abstract Background Sodium bicarbonate, in the form of baking soda, is widely used as a home remedy, and as an additive for personal and household cleaning products. Its toxicity has previously been reported following oral ingestion in the setting of dyspepsia. However, its use as a non-ingested agent, like a toothpaste additive, has not been reported as a potential cause of toxicity. Case presentation We are reporting a case of an 80-year-old woman who presented with chronic metabolic alkalosis and hypokalemia secondary to exogenous alkali exposure from baking soda as a toothpaste additive, which might have represented an underreported ingestion of the substance. Conclusions Considering that one teaspoon of baking soda provides approximately 59 m-equivalents (mEq) of bicarbonate, specific questioning on its general use should be pursued in similar cases of chloride resistant metabolic alkalosis.

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