Comparing Carotid Intima-Media Thicknessin Women with and Without Gestational Diabetes Mellitus

Abstract

Background & Aims: Women with history of gestational diabetes mellitus (GDM) are at risk for developing cardiovascular disease and metabolic syndrome. Carotid intima-media thickness (CIMT) is noninvasive marker of sub clinical atherosclerosis assessment. The aim of the present study was to assess relationship between GDM and increased CIMT. Methods: Twenty women with previous history of GDM and twenty women without it (as a control group) were included in the study. Two groups were matched based on their age, body mass index (BMI) and parity. CIMT was measured one year after delivery in two groups by B-mode sonography and compared with ultrasonic results of CIMT in mid- and late-gestational periods. Results: CIMT in both groups increased in gestational period and decreased after delivery and this diminution was significant at late-gestational period in both groups and also significant at mid-gestational period in women with history of GDM. Conclusion: CIMT wassignificantly decreased one year after delivery in women with GDM

Keywords

• carotid intima_media thickness
• gestational diabetes mellitus
• ultrasonography