Effects of main active components of rosemary on growth performance, meat quality and lipid metabolism in finishing pigs

Qianjin Zhang; Jiatai Gong; Hongkun Xiang; Ruizhi Hu; Xizi Yang; Jing Lv; Wentao Zhang; Ming Liu; Xiong Deng; Xupeng Yuan; Ziyu He; Yixuan Jiang; Bie Tan; Jianhua He; Shusong Wu

Animal Nutrition (Dec 2023)

Effects of main active components of rosemary on growth performance, meat quality and lipid metabolism in finishing pigs

Qianjin Zhang,
Jiatai Gong,
Hongkun Xiang,
Ruizhi Hu,
Xizi Yang,
Jing Lv,
Wentao Zhang,
Ming Liu,
Xiong Deng,
Xupeng Yuan,
Ziyu He,
Yixuan Jiang,
Bie Tan,
Jianhua He,
Shusong Wu

Affiliations

Qianjin Zhang: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Jiatai Gong: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Hongkun Xiang: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Ruizhi Hu: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Xizi Yang: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Jing Lv: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Wentao Zhang: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Ming Liu: Animal Science and Technology College, Beijing University of Agriculture, Beijing 102206, China
Xiong Deng: Animal Science and Technology College, Beijing University of Agriculture, Beijing 102206, China
Xupeng Yuan: College of Animal Science and Technology, Hunan Biological and Electromechanical Polytechnic, Changsha 410127, China
Ziyu He: Department of Food Science and Biotechnology, Faculty of Agriculture, Kagoshima University, Kagoshima 890 - 0065, Japan
Yixuan Jiang: Hunan Delore Group Co. Ltd., Changsha 410131, China
Bie Tan: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Jianhua He: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Shusong Wu: Hunan Collaborative Innovation Center for Utilization of Botanical Functional Ingredients, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China; Corresponding author.

Journal volume & issue: Vol. 15
pp. 341 – 349

Abstract

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Rosemary extracts have been widely used as feed additives in recent years. This study aimed to investigate the effects of rosmarinic acid (RA) and ursolic acid (UA), the main active components of rosemary, on growth performance, meat quality and lipid metabolism in finishing pigs. A total of 72 finishing pigs (Landrace; initial age of 150 d) were randomly divided into 3 treatments with 8 replicates of 3 pigs each, and fed a basal diet or diet containing 500 mg/kg of RA or UA. The results showed that dietary supplementation of RA or UA had no significant effect on the growth performance and carcass traits of finishing pigs (P > 0.05). However, both RA and UA significantly increased the triglyceride (TG) level in soleus muscle (P < 0.001). Supplementation of RA increased the expression of genes related to lipogenesis and transport including fatty acid synthase (FAS) (P < 0.001), sterol regulatory element binding protein-1c (SREBP1c) (P < 0.001) and peroxisome proliferator-activated receptor γ (PPARγ) (P < 0.05), while UA increased the expression of fatty acid transport protein 1 (FATP1), a gene related to lipid uptake (P < 0.05). However, RA reduced the expression of adipogenesis-related gene acetyl-coenzyme A carboxylase α (ACCα) (P < 0.01). Characterization of cecal microbiota indicated that RA increased the microbial richness (chao 1, P < 0.001) and diversity (observed species, P < 0.01). Further analysis of the genera revealed that RA increased the relative abundance of Bacteroides and g-UCG-005 (P < 0.05), and UA enriched Prevotella (P < 0.001). Correlation analysis showed that g-UCG-005 was positively correlated with the expression of FAS, carnitine palmitoyl transferase 1B (CPT1B), SREBP1c and PPARγ (P < 0.01). In conclusion, dietary supplementation of RA or UA may increase fat deposition in muscle of finishing pigs by regulating lipid metabolism and gut microbiota.

Published in Animal Nutrition

ISSN: 2405-6545 (Print)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Agriculture: Animal culture
Website: https://www.keaipublishing.com/en/journals/animal-nutrition/

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