Endogenous stimulus-powered antibiotic release from nanoreactors for a combination therapy of bacterial infections

Yang Wu; Zhiyong Song; Huajuan Wang; Heyou Han

doi:10.1038/s41467-019-12233-2

Nature Communications (Oct 2019)

Endogenous stimulus-powered antibiotic release from nanoreactors for a combination therapy of bacterial infections

Yang Wu,
Zhiyong Song,
Huajuan Wang,
Heyou Han

Affiliations

Yang Wu: State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University
Zhiyong Song: State Key Laboratory of Agricultural Microbiology, College of Science, Huazhong Agricultural University
Huajuan Wang: State Key Laboratory of Agricultural Microbiology, College of Food Science and Technology, Huazhong Agricultural University
Heyou Han: State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University

DOI: https://doi.org/10.1038/s41467-019-12233-2
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 10

Abstract

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Endogenous triggered delivery of antibiotics over an external triggered delivery has distinct advantages. Here, the authors report on a nanoreactor triggered by bacterial toxin to trigger a drug release mechanism and capture the toxin for reduced toxicity of toxins and improved immune response.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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