Nature Communications (Nov 2021)

Photo-induced catalytic halopyridylation of alkenes

  • Shi-Yu Guo,
  • Fan Yang,
  • Ting-Ting Song,
  • Yu-Qing Guan,
  • Xiang-Ting Min,
  • Ding-Wei Ji,
  • Yan-Cheng Hu,
  • Qing-An Chen

DOI
https://doi.org/10.1038/s41467-021-26857-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 9

Abstract

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The Mizoroki–Heck reaction and its reductive analogue are staples of organic synthesis, but the ensuing products often lack a chemical handle for further transformation. Here the authors present a method to add a heterocycle and transformable halide across a double bond via iridium photocatalysis.