Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus

Pedro Dorado-Morales; M. Pilar Garcillán-Barcia; Iñigo Lasa; Cristina Solano

doi:10.1128/mBio.03094-20

mBio (Feb 2021)

Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus

Pedro Dorado-Morales,
M. Pilar Garcillán-Barcia,
Iñigo Lasa,
Cristina Solano

Affiliations

Pedro Dorado-Morales: Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, Spain
M. Pilar Garcillán-Barcia: Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria—Consejo Superior de Investigaciones Científicas, Santander, Cantabria, Spain
Iñigo Lasa: ORCiD; Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, Spain
Cristina Solano: ORCiD; Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, Spain

DOI: https://doi.org/10.1128/mBio.03094-20
Journal volume & issue: Vol. 12, no. 1

Abstract

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Plasmids are major agents in the spread of antibiotic resistance genes among bacteria. How plasmids and their hosts coevolve to reduce the fitness cost associated with plasmid carriage when bacteria grow in an antibiotic-free environment is not well understood.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal