Analytical Cellular Pathology (Jan 2010)

EBV-Infection in Cardiac and Non-Cardiac Gastric Adenocarcinomas is Associated with Promoter Methylation of p16, p14 and APC, but not hMLH1

  • Helene Geddert,
  • Axel zur Hausen,
  • Helmut E. Gabbert,
  • Mario Sarbia

DOI
https://doi.org/10.3233/ACP-CLO-2010-0540
Journal volume & issue
Vol. 33, no. 3-4
pp. 143 – 149

Abstract

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Background: Epstein–Barr virus (EBV)-associated gastric carcinomas (GC) constitute a distinct clinicopathological entity of gastric cancer. In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV.