The effect of carotenoids of Rhodotorula glutinis and probiotic of Lactobacillus acidophilus on some physiological and histological variables of the pancreas and liver in male rats exposed to ultraviolet radiation.

Abstract

ABSTRACT This study was conducted in the laboratory animal house at the College of Education/University of Samarra to establish and evaluate and treatment the effect of ultraviolet radiation (UV) on the health and functions of the pancreas and liver by use the carotenoids that extracted from Rhodotorula glutinis yeast and Lactobacillus acidophilus as probiotic. 28 male laboratory rats were used and divided into four groups with 7 animals in each group, the experiment period 28 days, including 24 hours representing the period of exposure to ultraviolet radiation before treatment. The results showed significant increase (P˂0.05) in concentrations of glucose, cholesterol, triglycerides, bilirubin and activity of ALT, AST and ALP in group that exposed to ultraviolet radiation in compared with the healthy control group, whereas, observed significantly decrease of all previous parameters in the groups that treated with probiotic and the carotenoids in comparison with ultraviolet radiation group, and repair of the damage that occur in tissues of pancreas and liver result from the effect of ultraviolet rays.