Медицинская иммунология (Jul 2014)
INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS
Abstract
Abstract. The article contains results of studying the natural inhibitory serum activity in the patients with acute leukemia. A correlation is revealed between a resistance to myelosuppressive therapy, and positive inhibitory reaction towards immunoglobulins M. Determination of IL-2, IL-4 levels, as well as sulfhydril (SH- ) groups and amounts of blast cells at initial stage of disease are of high importance for early diagnosis of drug resistance upon the disease onset.
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