Correlation of Serum Ferritin with Lipid Profile in β-Thalassemia Patients

Abstract

Background: The present study was aimed to study alterations in lipid levels and its corelation with ferritin in Thalassemia patients. Methods: 50 patients of diagnosed Thalassemia in age group of 9 to 12 years were included in the study and results were compared with controls. Lipid profile and serum ferritin levels were estimated. Results: Significant (<0.05) decreased levels of Cholesterol, HDL-cholesterol, LDL- cholesterol, VLDL-cholesterol were found as compared to controls. Serum triglyceride & ferritin levels were significantly (<0.05) increased as compared to controls. Conclusion: The positive correlation between serum ferritin and Cholesterol, HDL, LDL, VLDL& negative correlation between serum ferritin & TG levels which may attribute to the future fatal cardiac complication. Thus, lipid profile monitoring as well as ferritin level are necessary to prevent or at least enhance the early detection of cardiac complications. So, ferritin can be used as a marker for prevention of cardiac complication.

Keywords

• Ferritin
• Lipid profile
• Thalassemia