Journal of Statistical Software (Aug 2012)

[download] (969)dlmap: An R Package for Mixed Model QTL and Association Analysis

  • B. Emma Huang,
  • Rohan Shah,
  • Andrew W. George

Journal volume & issue
Vol. 50, no. 6

Abstract

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dlmap is a software package capable of mapping quantitative trait loci (QTL) in a variety of genetic studies. Unlike most other QTL mapping packages, dlmap is built on a linear mixed model platform, and thus can simultaneously handle multiple sources of genetic and environmental variation. Furthermore, it can accommodate both experimental crosses and association mapping populations within a versatile modeling framework. The software implements a mapping algorithm with separate detection and localization stages in a user-friendly manner. It accepts data in various common formats, has a flexible modeling environment, and summarizes results both graphically and numerically.

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