Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients

Abstract

Matrix Gla protein (MGP) is a calcification inhibitor that plays a role in preventing soft tissue calcification and local mineralization of the vascular wall. The present study aimed to assess the expression of MGP in Peripheral Blood Mononuclear Cells (PBMC) in adult patients with CVD pathologies and its association with the presence and severity of coronary artery calcium score (CACS) and conventional CVD risk factors.

Keywords

• biomarkers
• cardiovascular disease
• gene expression
• matrix gla-protein
• peripheral blood mononuclear cells
• biyobelirteçler
• kardiyovasküler hastalık
• matrix gla-proteini
• gen ekspresyonu
• periferik kan mononükleer hücreleri