Frontiers in Chemistry (Aug 2021)

Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers

  • Zhenglei Xu,
  • Minsi Peng,
  • Zhuliang Zhang,
  • Haotian Zeng,
  • Ruiyue Shi,
  • Xiaoxin Ma,
  • Lisheng Wang,
  • Bihong Liao

DOI
https://doi.org/10.3389/fchem.2021.733371
Journal volume & issue
Vol. 9

Abstract

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Pancreatic cancer is a highly lethal gastrointestinal malignancy. Most patients are already in the middle to advanced stages of pancreatic cancer at the time of diagnosis and cannot be treated completely. As a single-atom planar two-dimensional crystal, graphene’s unusual electronic structure, specific electronic properties and excellent electron transport capacity make it uniquely advantageous in the field of electrochemical sensing. In this mini-review, we summarize the potential application of graphene in pancreatic cancer detection. K-Ras gene, CEA and MicroRNA are important in the early diagnosis of pancreatic cancer.

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