Patient-Specific Bone Multiscale Modelling, Fracture Simulation and Risk Analysis—A Survey

Amadeus  C. S. Alcântara; Israel Assis; Daniel Prada; Konrad Mehle; Stefan Schwan; Lúcia Costa-Paiva; Munir  S. Skaf; Luiz  C. Wrobel; Paulo Sollero

doi:10.3390/ma13010106

Materials (Dec 2019)

Patient-Specific Bone Multiscale Modelling, Fracture Simulation and Risk Analysis—A Survey

Amadeus C. S. Alcântara,
Israel Assis,
Daniel Prada,
Konrad Mehle,
Stefan Schwan,
Lúcia Costa-Paiva,
Munir S. Skaf,
Luiz C. Wrobel,
Paulo Sollero

Affiliations

Amadeus C. S. Alcântara: Department of Computational Mechanics, School of Mechanical Engineering, University of Campinas—UNICAMP, Campinas, Sao Paulo 13083-860, Brazil
Israel Assis: Department of Integrated Systems, School of Mechanical Engineering, University of Campinas—UNICAMP, Campinas, Sao Paulo 13083-860, Brazil
Daniel Prada: Department of Computational Mechanics, School of Mechanical Engineering, University of Campinas—UNICAMP, Campinas, Sao Paulo 13083-860, Brazil
Konrad Mehle: Department of Engineering and Natural Sciences, University of Applied Sciences Merseburg, 06217 Merseburg, Germany
Stefan Schwan: Fraunhofer Institute for Microstructure of Materials and Systems IMWS, 06120 Halle/Saale, Germany
Lúcia Costa-Paiva: Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas—UNICAMP, Campinas, Sao Paulo 13083-887, Brazil
Munir S. Skaf: Institute of Chemistry and Center for Computing in Engineering and Sciences, University of Campinas—UNICAMP, Campinas, Sao Paulo 13083-860, Brazil
Luiz C. Wrobel: Institute of Materials and Manufacturing, Brunel University London, Uxbridge UB8 3PH, UK
Paulo Sollero: Department of Computational Mechanics, School of Mechanical Engineering, University of Campinas—UNICAMP, Campinas, Sao Paulo 13083-860, Brazil

DOI: https://doi.org/10.3390/ma13010106
Journal volume & issue: Vol. 13, no. 1
p. 106

Abstract

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This paper provides a starting point for researchers and practitioners from biology, medicine, physics and engineering who can benefit from an up-to-date literature survey on patient-specific bone fracture modelling, simulation and risk analysis. This survey hints at a framework for devising realistic patient-specific bone fracture simulations. This paper has 18 sections: Section 1 presents the main interested parties; Section 2 explains the organzation of the text; Section 3 motivates further work on patient-specific bone fracture simulation; Section 4 motivates this survey; Section 5 concerns the collection of bibliographical references; Section 6 motivates the physico-mathematical approach to bone fracture; Section 7 presents the modelling of bone as a continuum; Section 8 categorizes the surveyed literature into a continuum mechanics framework; Section 9 concerns the computational modelling of bone geometry; Section 10 concerns the estimation of bone mechanical properties; Section 11 concerns the selection of boundary conditions representative of bone trauma; Section 12 concerns bone fracture simulation; Section 13 presents the multiscale structure of bone; Section 14 concerns the multiscale mathematical modelling of bone; Section 15 concerns the experimental validation of bone fracture simulations; Section 16 concerns bone fracture risk assessment. Lastly, glossaries for symbols, acronyms, and physico-mathematical terms are provided.

Published in Materials

ISSN: 1996-1944 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering; Technology: Engineering (General). Civil engineering (General); Science: Natural history (General): Microscopy; Science: Physics: Descriptive and experimental mechanics
Website: http://www.mdpi.com/journal/materials/

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