AIDS Research and Therapy (Oct 2012)

ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14

  • Rosen Marc I,
  • Black Anne C,
  • Arnsten Julia H,
  • Simoni Jane M,
  • Wagner Glann J,
  • Goggin Kathleen,
  • Remien Robert H,
  • Golin Carol E,
  • Wang Yan,
  • Bangsberg David,
  • Liu Honghu H

DOI
https://doi.org/10.1186/1742-6405-9-30
Journal volume & issue
Vol. 9, no. 1
p. 30

Abstract

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Abstract Background Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on adherence is unknown. Findings In this study, 215 patients who had been in adherence-focused research studies provided electronically-measured adherence data and a measure of whether the patient had recently been in substance abuse treatment. Recent engagement in substance abuse treatment was independently associated with significantly higher adherence, after covarying for recent substance use and other factors potentially affecting adherence. Conclusions The findings suggest that substance abuse treatment is associated with better adherence. Potential mechanisms by which substance abuse treatment improves adherence, such as more stability or more future-orientation, require further study.

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