ACS Central Science (Jan 2019)
A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
- Joshua J. Woods,
- Neeharika Nemani,
- Santhanam Shanmughapriya,
- Akshay Kumar,
- MengQi Zhang,
- Sarah R. Nathan,
- Manfred Thomas,
- Edmund Carvalho,
- Karthik Ramachandran,
- Subramanya Srikantan,
- Peter B. Stathopulos,
- Justin J. Wilson,
- Muniswamy Madesh
Affiliations
- Joshua J. Woods
- Robert F. Smith School for Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York, United States
- Neeharika Nemani
- Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States
- Santhanam Shanmughapriya
- Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States
- Akshay Kumar
- Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States
- MengQi Zhang
- Department of Physiology and Pharmacology, Western University, London, Ontario, Canada
- Sarah R. Nathan
- Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States
- Manfred Thomas
- Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States
- Edmund Carvalho
- Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States
- Karthik Ramachandran
- Department of Medicine/Nephrology, Institute for Precision Medicine and Health, University of Texas Health San Antonio, San Antonio, Texas, United States
- Subramanya Srikantan
- Department of Medicine/Nephrology, Institute for Precision Medicine and Health, University of Texas Health San Antonio, San Antonio, Texas, United States
- Peter B. Stathopulos
- Department of Physiology and Pharmacology, Western University, London, Ontario, Canada
- Justin J. Wilson
- Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United States
- Muniswamy Madesh
- Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States
- DOI
- https://doi.org/10.1021/acscentsci.8b00773
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 153 – 166
Abstract
No abstracts available.