MAPK-dependent hormonal signaling plasticity contributes to overcoming Bacillus thuringiensis toxin action in an insect host

Zhaojiang Guo; Shi Kang; Dan Sun; Lijun Gong; Junlei Zhou; Jianying Qin; Le Guo; Liuhong Zhu; Yang Bai; Fan Ye; Qingjun Wu; Shaoli Wang; Neil Crickmore; Xuguo Zhou; Youjun Zhang

doi:10.1038/s41467-020-16608-8

Nature Communications (Jun 2020)

MAPK-dependent hormonal signaling plasticity contributes to overcoming Bacillus thuringiensis toxin action in an insect host

Zhaojiang Guo,
Shi Kang,
Dan Sun,
Lijun Gong,
Junlei Zhou,
Jianying Qin,
Le Guo,
Liuhong Zhu,
Yang Bai,
Fan Ye,
Qingjun Wu,
Shaoli Wang,
Neil Crickmore,
Xuguo Zhou,
Youjun Zhang

Affiliations

Zhaojiang Guo: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Shi Kang: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Dan Sun: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Lijun Gong: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Junlei Zhou: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Jianying Qin: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Le Guo: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Liuhong Zhu: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Yang Bai: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Fan Ye: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Qingjun Wu: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Shaoli Wang: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences
Neil Crickmore: School of Life Sciences, University of Sussex
Xuguo Zhou: Department of Entomology, University of Kentucky
Youjun Zhang: Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences

DOI: https://doi.org/10.1038/s41467-020-16608-8
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 14

Abstract

Read online

Bacillus thuringiensis (Bt) is an important bioinsecticide, but high-level resistance has been rapidly evolving in agricultural pests. Here, Guo et al. show that the MAPK cascade can be activated by enhanced upstream insect hormone signals to counter Bt virulence in the diamondback moth.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal