Allosteric Signal within the Receptor-Binding Domain of the SARS-CoV‑2 Spike Protein Mediated by a Class 3 Monoclonal Antibody Revealed through Molecular Dynamics Simulations and Protein Residue Networks

• Patamalai Boonserm,
• Wasusit Somsoros,
• Pongsak Khunrae,
• Krit Charupanit,
• Praopim Limsakul,
• Thana Sutthibutpong

Affiliations

Patamalai Boonserm

Department of Microbiology, Faculty of Science, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand

Wasusit Somsoros

Department of Microbiology, Faculty of Science, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand

Pongsak Khunrae

Department of Microbiology, Faculty of Science, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand

Krit Charupanit

Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand

Praopim Limsakul

Division of Physical Science, Faculty of Science, Prince of Songkla University, Songkhla, Thailand

Thana Sutthibutpong

Theoretical and Computational Physics Group, Department of Physics, Faculty of Science, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand