Journal of the Scientific Society (Jan 2023)

A short review on black fungal mucormycosis accompanied by Post-SARS-CoV-2

  • Abhishek Lachyan,
  • Vijay Kumar Singh,
  • Swati Verma,
  • Debashish Paramanick

DOI
https://doi.org/10.4103/jss.jss_86_21
Journal volume & issue
Vol. 50, no. 2
pp. 139 – 146

Abstract

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Many people who have recovered from coronavirus disease 2019 (COVID-19) have recently been diagnosed with black fungus – or mucormycosis – disease. Rhino-orbital mucormycosis is becoming more common in people with COVID-19, particularly in India. On its own, diabetes mellitus is a risk factor for severe COVID-19 and mucormycosis. The goal of this study is to conduct a review of the literature to determine the features of patients with mucormycosis and COVID-19. Increased mucormycosis in India appears to be the result of an unholy trifecta of diabetes (high hereditary incidence), corticosteroid overuse (increased blood glucose and opportunistic fungal infection), and COVID-19 (cytokine storm, lymphopenia, and endothelial damage). To limit the incidence of deadly mucormycosis, all efforts should be made to maintain optimum hyperglycemia, and only prudent evidence-based use of corticosteroids in patients with COVID-19 is advocated. In this review, we emphasize knowledge on diagnosis and therapy regarding black fungal mucormycosis, which is accompanied by post-SARS-CoV-2.

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