Association Between Overweight/Obesity and ART Drug Regimen Among Adult HIV Patients in Gamo Zone Public Health Facilities Southern Ethiopia

Abstract

Nigus Kabtu Belete, Darik Temesgen Assefa, Tesfaye Feleke Gadore, Manaye Yihune Teshale, Eshetu Zerihun Tariku School of Public Health, College of Medicine and Health Science, Arba Minch University, Arba Minch, EthiopiaCorrespondence: Nigus Kabtu Belete, Tel [phone], Email [email protected]: Overweight/obesity is an emerging public health problem in low income countries. Currently sub-Saharan African countries are facing a double burden of malnutrition. Evidence has shown that overweight/obesity is becoming a problem for people living with HIV. But little is known in our setting. Thus, this study is designed to assess the association between overweight/obesity and ART drug regimen among adult HIV patients in Gamo zone public health facilities southern Ethiopia.Objective: To assess the association between overweight/obesity and ART drug regimen among adult HIV patients in Gamo zone public health facilities southern Ethiopia.Methods: Institution-based cross-sectional study was conducted from April 10 to May 10, 2022, among systematically selected adult HIV patients. The data were collected by using a structured interviewer-administered questionnaire, patient record review, and physical measurements. Multivariate logistic regression model was used to assess the association between dependent and independent variables. A p-value < 0.05 with its 95% CI was considered as a statistically significant and interpreted accordingly.Results: The magnitude of overweight/obesity were 13.5% (95% CI:(10.4– 17.2)). Being male (2.484(1.308, 4.716)), duration on ART (took for ≥ 5 years) ((2.249(1.218, 4.152)), and ART drug regime (3.789(1.965, 7.304)) were significantly associated with overweight/obesity.Conclusion: Overweight/obesity is significantly associated to ART drug regimen type among adult HIV patients. Furthermore, sex and duration on ART drug were found significantly associated with overweight/obesity of adult HIV patients.Keywords: obesity, overweight, HIV, anti-retroviral therapy, drug, Gamo zone, Ethiopia

Keywords

• obesity
• overweight
• hiv
• anti-retroviral therapy
• drug
• gamo zone
• ethiopia