Lignan Glucosides from the Stem Barks of Illicium difengpi

Abstract

In this study, four new lignan glucosides, named difengpiosides A–D (1–4), were isolated from the stem barks of Illicium difengpi, together with seven known compounds 5–11. Their structures were identified on the basis of spectroscopic analyses (1D and 2D NMR, HRESIMS, CD) and a comparison with literature data. All the compounds were evaluated for their inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells.

Keywords

• Illicium difengpi
• stem barks
• lignan glucosides
• difengpiosides A–D
• NO inhibition