Investigation of some biochemical parameters in bitches with malignant mammary tumors

Abstract

Aim: This study, the cut-off point of biochemical parameters in bitches with mammary tumors was determined and its usability as a biomarker for diagnosis was investigated. Materials and Methods: Bitches that presented to our clinic for routine ovariohysterectomy (control group, n = 14) and suffer from mammary tumors (CMT group, n = 14) were included in the study. Biochemical parameters including albümin (ALB), alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gammaglutamyltransferase (GGT), total protein (TP), direct bilirubin (DB), total bilirubin (TP), creatine, creatine kinase-N-acetyl-cysteine (CK-NAC), urea, phosphorus (P), magnesium (Mg), and calcium (Ca) concentrations were measured with an automated chemistry analyzer. Results: The ALP (p: 0.048), ALT (p 0.05). It was seen that ALP, ALT, AST, GGT, TP, and creatine concentrations could be used to diagnose mammary tumors, with area under the curve (AUC) values of 0.656, 0.831, 0.610, 0.792, 0.942, and 0.974, respectively. Conclusion: It was concluded that ALP, ALT, AST, GGT, TP, and creatine could be helpful diagnostic tools for canine mammary tumors.

Keywords

• biochemical parameters
• bitch
• mammary tumors