Nature Communications (Dec 2021)

Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury

  • Daniel Jun-Kit Hu,
  • Jina Yun,
  • Justin Elstrott,
  • Heinrich Jasper

DOI
https://doi.org/10.1038/s41467-021-27384-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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Stem cell migration is critical during adult tissue regeneration. Here, the authors demonstrate that enteroendocrine cells coordinate stem cell migration towards sites of injury in the Drosophila intestine by activating non-canonical Wnt signaling.