ADMINISTRATION CRITERIA FOR INTERFERON-BASED DRUGS AND ITS INDUCERS IN ACUTE RESPIRATORY INFECTIONS IN CHILDREN

Abstract

Abstract. Interferon profile was studied in 412 children and 41 adults with acute respiratory virus infections, as well as in forty-eight healthy children and ninety-nine adults. Appropriate interrelations were evaluated between interferon contents, and age, specific clinical features, etiology and clinical course of the disease. Therapeutic efficiency of interferons and interferon inducers was studied at 928 children. Some novel parameters are proposed to assess interferon state, i.e., stimulation index of interferon production, and interferon-producing activity of lymphocytes that represent individual functional activity of the patients’ immunocompetent cells. Criteria for interferon administration.

Keywords

• interferon
• interferon inducers
• clinical effect
• immunological criteria