Бюллетень сибирской медицины (Feb 2011)
The experience of oxalate nephrolithiasis therapy by sodium pyrophosphate in experiment
Abstract
The aim of the investigation was studying sodium pyrophosphate’s effect on experimental oxalate nephrolithiasis.Experimental nephrolithiasis modeling by using of 1% ethylenglycole’s solution as a drink for rats during 6 weeks. First group was control. In the second group since the third week was being administrated sodium pyrophosphate in dose 2 g/kg. Was detecting parameters of kidney’s function, markers enzymes activity, was carried out morphological researches.It was concluded that sodium pyrophosphate’s therapy reduce experimental oxalate nephrolithiasis.
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