Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging

Abstract

It was recently shown that basal cells in pseudostratified epithelia extend a long cytoplasmic process across the tight junction barrier into the lumen. Here Roy & Kim et al. show that these projections, which they call axiopodia, extend and retract over time in a c-Src and MEK-ERK-dependent manner.