Revisiting diosmin for their potential biological properties and applications

Abstract

Diosmin is a well-known naturally occurring flavonoid that is used to treat diseased veins and chronic blood vessel insufficiency. A comprehensive investigation conducted recently has revealed that diosmin has a wide range of medical specialty properties, including anti-oxidant, anti-diabetic, anti-cancer, anti-microorganism, liver protection, neuroprotection, vascular protection, and retinal protection properties. Its use in therapeutic settings is severely limited. As anticipated, a multitude of possible approaches have been developed to enhance its pharmacokinetic properties and bioavailability. It has been investigated as a significant part of the micronized purified flavonoid fraction (MPFF), which has been utilized in centers toward work on miniature flow. In any case, no particular medication focuses for diosmin are accounted for albeit some potential elements have been associated with screening. More examinations on the basic systems of diosmin in intervening cell processes with high explicitness are as yet required. This compound demonstrates anti-lipid peroxidation, anti-inflammatory, antioxidant, and anti-mutagenic properties, making it a valuable component in addressing oxidative stress and suboptimal inflammation. As one of the flavonoids employed in medicinal contexts, its pharmacological intricacies remain a complex area of exploration. While diosmin has shown promise in multiple applications, there is still a considerable distance to cover in achieving a comprehensive understanding of its pharmacology for practical clinical use. In this review article, we examined diosmin measures and their applications.

Keywords

• Diosmin
• Cancel cell
• Liver
• Kidney
• Rats