Assumption Checking Before Application of the Prespecified QT Linear Mixed Effect Model is Essential

• Dinko Rekić,
• Joanna Parkinson,
• Holly Kimko

Affiliations

Dinko Rekić

Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences R&D, AstraZeneca Gothenburg Sweden

Joanna Parkinson

Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences R&D, AstraZeneca Gothenburg Sweden

Holly Kimko

Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences R&D, AstraZeneca Gaithersburg Maryland USA