RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)

Abstract

Presented article is a review of domestic and foreign literature on the application of radiomodifying drugs with electron-affinic properties (metronidazole and its derivatives) with the aim of increasing the effectiveness of radiation therapy. The mechanism of action and properties of the electron-affinic drugs of is described. Special attention is paid to the creation of a new medicinal form of metronidazole with the hydrogel-based biopolymer and its inclusion in combined treatment of resectable and locally advanced rectal cancer.

Keywords

• electronacceptor compounds
• metronidazole and its derivatives