Nature Communications (Oct 2019)

The rostroventral part of the thalamic reticular nucleus modulates fear extinction

  • Joon-Hyuk Lee,
  • Charles-Francois V. Latchoumane,
  • Jungjoon Park,
  • Jinhyun Kim,
  • Jaeseung Jeong,
  • Kwang-Hyung Lee,
  • Hee-Sup Shin

DOI
https://doi.org/10.1038/s41467-019-12496-9
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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The precise role of the thalamic reticular nucleus in fear is not understood. Here, the authors report that the rostroventral part of the reticular nucleus is involved in the extinction of tone conditioned fear memory through its inhibitory projections to the dorsal midline thalamus.