Nature Communications (May 2020)

The DNA methylation landscape of giant viruses

  • Sandra Jeudy,
  • Sofia Rigou,
  • Jean-Marie Alempic,
  • Jean-Michel Claverie,
  • Chantal Abergel,
  • Matthieu Legendre

DOI
https://doi.org/10.1038/s41467-020-16414-2
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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DNA methylation is an epigenetic marker in all domains of life. Here, Jeudy et al., using single-molecule realtime sequencing, determine DNA methylation patterns in giant viruses and evolutionary analysis of virus encoded DNA methyltransferases suggests that they affect viral fitness.