Factors Affecting Optimal Continuous Positive Airway Pressure Level in Patients with Obstructive Sleep Apnea Syndrome

Abstract

Abstract Objectives: This study aimed to examine factors (BMI, neck circumference, AHI etc.) affecting optimal CPAP levels in patients with obstructive sleep apnea syndrome (OSAS). Materials and Methods: A total of 120 patients with OSAS who underwent successful auto-titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data were analyzed. Results: The mean optimal pressure level in the 120 OSAS patients was 9.11 ± 2.81 cm H2O. The mean optimal pressure levels in the mild, moderate, and severe OSAS groups were 8.01 ± 2.60, 8.32 ± 2.22, and 9.71 ± 3.01 cm H2O, respectively. Apnea/hypopnea index (AHI) (r=0.297, p lt;0.001) and minimal SaO2 (r=-0.264, p lt;0.004) were significantly correlated with optimal pressure level. 22 patients in the titration failure group had severe AHI overall; 6 patients had REM-related and 2 had position-related OSAS. Patients in the titration failure group who did not have a specific diagnosis (rapid eye movement (REM) or positional OSAS) had very severe AHI levels (mean AHI of 67.90). Conclusion: According to the correlation tests, AHI and the lowest saturation were the two most important predictors of optimal CPAP level.

Keywords

• obstrüktif uyku apne sendromu
• sürekli pozitif havayolu basıncı
• apne
• polisomnografi
• obstructive sleep apnea syndrome
• continuous positive airway pressure
• apnea
• polysomnography