Nature Communications (Jan 2024)

Robustly federated learning model for identifying high-risk patients with postoperative gastric cancer recurrence

  • Bao Feng,
  • Jiangfeng Shi,
  • Liebin Huang,
  • Zhiqi Yang,
  • Shi-Ting Feng,
  • Jianpeng Li,
  • Qinxian Chen,
  • Huimin Xue,
  • Xiangguang Chen,
  • Cuixia Wan,
  • Qinghui Hu,
  • Enming Cui,
  • Yehang Chen,
  • Wansheng Long

DOI
https://doi.org/10.1038/s41467-024-44946-4
Journal volume & issue
Vol. 15, no. 1
pp. 1 – 11

Abstract

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Abstract The prediction of patient disease risk via computed tomography (CT) images and artificial intelligence techniques shows great potential. However, training a robust artificial intelligence model typically requires large-scale data support. In practice, the collection of medical data faces obstacles related to privacy protection. Therefore, the present study aims to establish a robust federated learning model to overcome the data island problem and identify high-risk patients with postoperative gastric cancer recurrence in a multicentre, cross-institution setting, thereby enabling robust treatment with significant value. In the present study, we collect data from four independent medical institutions for experimentation. The robust federated learning model algorithm yields area under the receiver operating characteristic curve (AUC) values of 0.710, 0.798, 0.809, and 0.869 across four data centres. Additionally, the effectiveness of the algorithm is evaluated, and both adaptive and common features are identified through analysis.