Journal of Investigative Medicine High Impact Case Reports (Apr 2022)

Status Epilepticus Following Intrathecal Administration of Bupivacaine: A Case Report

  • Arthur Vanmarcke,
  • Piet Lormans,
  • Catherine Vandewaeter

DOI
https://doi.org/10.1177/23247096221090841
Journal volume & issue
Vol. 10

Abstract

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Spinal anesthesia is common practice and rarely causes complications. Although extended experience is present, seldom side effects of this technique and the administration of intrathecal local anesthetics and/or opioids can occur. We present a case in which a 76-year old woman undergoing total hip arthroplasty received a low dose of intrathecal bupivacaine and sufentanil. One hour after administration, she developed myoclonic seizures of the lower extremities followed by generalized tonic-clonic seizures and status epilepticus. We conclude that status epilepticus is a rare and possible lethal side effect of intrathecal bupivacaine. Symptoms may be misleading, highlighting the importance of early recognition and adequate management.