Generation of an integration-free iPSC line(SYSUi001-A) from a sporadic Alzheimer's disease patient

Rui Wei; Hongying Han; Mingxin Ye; Lu He; Qingfeng Lei; Tiancheng Zhou; Xiujuan Cai; Zhong Li

Stem Cell Research (Mar 2019)

Generation of an integration-free iPSC line(SYSUi001-A) from a sporadic Alzheimer's disease patient

Rui Wei,
Hongying Han,
Mingxin Ye,
Lu He,
Qingfeng Lei,
Tiancheng Zhou,
Xiujuan Cai,
Zhong Li

Affiliations

Rui Wei: Department of Neurology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Rd, Guangzhou 510655, PR China
Hongying Han: Department of Psychiatry, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd, Guangzhou 510630, PR China
Mingxin Ye: Department of Neurology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Rd, Guangzhou 510655, PR China
Lu He: Department of Neurology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Rd, Guangzhou 510655, PR China
Qingfeng Lei: Department of Neurology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Rd, Guangzhou 510655, PR China
Tiancheng Zhou: Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, PR China
Xiujuan Cai: Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, PR China
Zhong Li: Department of Neurology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Rd, Guangzhou 510655, PR China; Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Shenzhen Research Institute of Sun Yat-Sen University, Southern District of Nanshan Science Park, Shenzhen 518019, PR China; Corresponding author at: Neurology Department, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Road, Guangzhou 510655, PR China.

Journal volume & issue: Vol. 35

Abstract

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Human iPSC line, iPSC-ADM01(SYSUi001-A), was generated from a 70-year-old male patient with sporadic Alzheimer's disease, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and in vivo, and has a normal karyotype.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

About the journal