Methyl 2-{[(4-hydroxyphenyl)(methoxycarbonyl)methyl]aminocarbonyl}ethanoate hemihydrate

Abstract

In the structure of the title compound, C13H15NO6·0.5H2O, the water O atom lies on a twofold rotation axis. The methoxycarbonylmethyl and amino groups are essentially coplanar and the methoxycarbonylmethyl group makes a dihedral angle of 79.73 (10)° with the mean plane of the hydroxyphenyl ring. The amino and methoxycarbonylmethyl groups are involved in an intramolecular N—H...O hydrogen bond which generates an S(5) ring motif. In the crystal structure, molecules are linked via N—H...O and O—H...O hydrogen bonds and weak C—H...O interactions into a two-dimensional network parallel to the (overline{2}01) plane. The crystal structure is further stabilized by C—H...π interactions.