Compostos de platina em quimioterapia do câncer Platinum complexes in cancer chemotherapy

Abstract

The vast majority of clinically used antitumor drugs are either synthetic or natural product based organic compounds. In this review we describe different aspects, such as structure-activity relationships, mechanism of action, clinical uses and possible future prospects, of the platinum antitumor complexes, a distinct class of antitumor agents.

Keywords

• platinum complexes
• structure-activity relationships of platinum-amine complexes
• antitumor agents