Российский кардиологический журнал (Dec 2014)
CARDIAC ARRHYTHMIAS AND CARDIOHEMODYNAMIC DISORDERS IN PATIENTS WITH VIRAL LIVER CIRRHOSIS
Abstract
Aim. To study the influence of viral liver cirrhosis on prevalence, typers of arrhythmias and some cardiohemodynamic parameters.Material and methods. Totally 75 patients studied with viral cirrhosis classes A, B, C by Child-Piugh. Patients were divided into 2 groups: with ascitis and without, controls consisted of 19 healthy volunteers. Doppler echo-study, Doppler tissuestudy were used, as Holter monitoring of ECG, and QT dispersion was calculated.Results. In patients with viral cirrhosis of the liver we found the increase of mean daily heartrate, disordered segmentary diastolic dysfunction and global longitudinal systolic function of the ventricle, increase of the left atrium volume with rhythm disorders and conduction disorders formation: QT becomes longer, heart rate variability decreases, p<0,001. These disorders are more prominent in ascitis patients. In all patients with viral cirrhosis the study of interdependence of structurefunctional parameters and heart rate variability was done.Conclusion. In liver cirrhosis patients of viral ethiology we found the increase of the left atrium, rhythm and conduction disorders, QT interval prolongation, heart rate variability decrease, as global longitudinal systolic function of ventricles. These changes are more prominent in ascitis patients.
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