Synthesis and antifungal activity of 3-aryl-1-(5-phenyl-1H-tetrazol-1-yl)prop-2-en-1-One

Abstract

5-phenyl 1-acetyl tetrazole were allowed to react separately with different aromatic aldehydes in presence of alkaline medium to yield corresponding 5-phenyl tetrazole 1- substituted chalcones.The compounds were identified by spectral data and screened for in-vitro antifungal activity by using cup and plate method.

Keywords

• 5-phenyl tetrazole
• chalcone
• antifungal activity