Current Directions in Biomedical Engineering (Dec 2023)

Consideration of Kv ion channels as firstorder systems

  • Lozanović Jasmina,
  • Langthaler Sonja,
  • Rienmüller Theresa Margarethe,
  • Polz Mathias,
  • Ziesel Daniel,
  • Schröttner Jörg,
  • Baumgartner Christian

DOI
https://doi.org/10.1515/cdbme-2023-1209
Journal volume & issue
Vol. 9, no. 2
pp. 31 – 33

Abstract

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This paper discusses possibilities to explain which Kv channels can be considered as first-order systems. This means that the dynamic behavior of these channels can be described with a first-order differential equation and are the most straightforward dynamical systems. For example, a typical first-order system is an RC circuit, and analogously, Kv channels can be considered with the dynamic behavior of first-order systems following RC circuits. This work represents a family of KV channels that can be described as first-order systems, providing an efficient method of ion channel modeling in computational electrophysiology.

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