Diagnostics (Feb 2023)

Diagnosis of Uric Acid-Based Urine Sedimentation in the Bladder Using Dual-Energy CT

  • Christian Booz,
  • Ibrahim Yel,
  • Julian L. Wichmann,
  • Simon S. Martin,
  • Vitali Koch,
  • Leon D. Gruenewald,
  • Leona S. Alizadeh,
  • Thomas J. Vogl,
  • Tommaso D’Angelo

DOI
https://doi.org/10.3390/diagnostics13030542
Journal volume & issue
Vol. 13, no. 3
p. 542

Abstract

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Urine sedimentation in the bladder can occur in various circumstances and can lead to urinary obstruction/stasis with associated pain. It is usually diagnosed with an ultrasound; however, CT is also used to assess the amount and to further check for urinary stones. Depending on the composition, urine sedimentation and stones can be treated medically by alkalinisation of the urine with potassium sodium hydrogen citrate in the case of uric acid-based sedimentation/stones. Due to technical developments and improved material differentiation and characterisation in CT imaging, dual-energy CT allows for differentiation of uric acid from calcium, which can be used for sedimentation/stone composition analysis. Subsequently, treatment decisions can be made based on the findings in dual-energy CT.

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