Nature Communications (Nov 2021)
A Brainstem reticulotegmental neural ensemble drives acoustic startle reflexes
- Weiwei Guo,
- Sijia Fan,
- Dan Xiao,
- Hui Dong,
- Guangwei Xu,
- Zhikun Wan,
- Yuqian Ma,
- Zhen Wang,
- Tian Xue,
- Yifeng Zhou,
- Yulong Li,
- Wei Xiong
Affiliations
- Weiwei Guo
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Sijia Fan
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Dan Xiao
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Hui Dong
- State Key Laboratory of Membrane Biology, Peking University School of Life Sciences
- Guangwei Xu
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Zhikun Wan
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Yuqian Ma
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Zhen Wang
- Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine
- Tian Xue
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Yifeng Zhou
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- Yulong Li
- State Key Laboratory of Membrane Biology, Peking University School of Life Sciences
- Wei Xiong
- Institute on Aging and Brain Disorders, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
- DOI
- https://doi.org/10.1038/s41467-021-26723-9
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 12
Abstract
The function of brainstem reticulotegmental nucleus (RtTg) and its related circuits are not fully understood. Here, the authors report a cochlear nucleus-RtTg-spinal motor neuron circuit that specifically mediates acoustic startle reflexes.