Quality of life among people living with HIV/AIDS receiving highly active anti-retroviral therapy: A domain-based analysis

Abstract

Introduction: With the highly effective antiretroviral treatment, HIV is transforming into a chronic condition, whose management is now experiencing problems of other chronic diseases, where quality of life (QoL) plays a central role. This study was conducted with the objective of determining the QoL among people living with HIV/AIDS (PLHA) taking Anti-Retroviral Therapy (ART) and examine the factors affecting it. Material and Methods: A cross-sectional study was conducted at ART center, Aligarh. 434 PLHA on antiretroviral therapy, were interviewed using a pretested questionnaire, assessing QoL with the World Health Organization (WHOQoL) HIV-BREF. For domain-based analysis, we examined the association of various factors with the individual domain. The P < 0.05 was considered statistically significant. Results: The mean score in all the domains of WHOQoL was maximum for the level of independence (15.7 ± 2.6) followed by the physical domain (15.5 ± 3.0), while environment domain (11.7 ± 1.8) had the least mean. All the domains, including overall QoL scored above average QoL. This study also showed that a strong relationship exists between QoL with lower socioeconomic status, presence of side effects from ART and depression. Conclusion: The QoL of HIV patients taking ART from Aligarh was adequate, reflecting the efforts of NACO and other agencies in managing the disease. With respect to its determinants, providing good family support, better employment opportunities, reducing stigma, and proper and timely management of side effects and depression could further increase levels of QoL.

Keywords

• antiretroviral therapy
• hiv/aids
• people living with hiv/aids
• quality of life
• world health organization quality of life