Nature Communications (Jul 2017)
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
- M. Carola Zillikens,
- Serkalem Demissie,
- Yi-Hsiang Hsu,
- Laura M. Yerges-Armstrong,
- Wen-Chi Chou,
- Lisette Stolk,
- Gregory Livshits,
- Linda Broer,
- Toby Johnson,
- Daniel L. Koller,
- Zoltán Kutalik,
- Jian’an Luan,
- Ida Malkin,
- Janina S. Ried,
- Albert V. Smith,
- Gudmar Thorleifsson,
- Liesbeth Vandenput,
- Jing Hua Zhao,
- Weihua Zhang,
- Ali Aghdassi,
- Kristina Åkesson,
- Najaf Amin,
- Leslie J. Baier,
- Inês Barroso,
- David A. Bennett,
- Lars Bertram,
- Rainer Biffar,
- Murielle Bochud,
- Michael Boehnke,
- Ingrid B. Borecki,
- Aron S. Buchman,
- Liisa Byberg,
- Harry Campbell,
- Natalia Campos Obanda,
- Jane A. Cauley,
- Peggy M. Cawthon,
- Henna Cederberg,
- Zhao Chen,
- Nam H. Cho,
- Hyung Jin Choi,
- Melina Claussnitzer,
- Francis Collins,
- Steven R. Cummings,
- Philip L. De Jager,
- Ilja Demuth,
- Rosalie A. M. Dhonukshe-Rutten,
- Luda Diatchenko,
- Gudny Eiriksdottir,
- Anke W. Enneman,
- Mike Erdos,
- Johan G. Eriksson,
- Joel Eriksson,
- Karol Estrada,
- Daniel S. Evans,
- Mary F. Feitosa,
- Mao Fu,
- Melissa Garcia,
- Christian Gieger,
- Thomas Girke,
- Nicole L. Glazer,
- Harald Grallert,
- Jagvir Grewal,
- Bok-Ghee Han,
- Robert L. Hanson,
- Caroline Hayward,
- Albert Hofman,
- Eric P. Hoffman,
- Georg Homuth,
- Wen-Chi Hsueh,
- Monica J. Hubal,
- Alan Hubbard,
- Kim M. Huffman,
- Lise B. Husted,
- Thomas Illig,
- Erik Ingelsson,
- Till Ittermann,
- John-Olov Jansson,
- Joanne M. Jordan,
- Antti Jula,
- Magnus Karlsson,
- Kay-Tee Khaw,
- Tuomas O. Kilpeläinen,
- Norman Klopp,
- Jacqueline S. L. Kloth,
- Heikki A. Koistinen,
- William E. Kraus,
- Stephen Kritchevsky,
- Teemu Kuulasmaa,
- Johanna Kuusisto,
- Markku Laakso,
- Jari Lahti,
- Thomas Lang,
- Bente L. Langdahl,
- Lenore J. Launer,
- Jong-Young Lee,
- Markus M. Lerch,
- Joshua R. Lewis,
- Lars Lind,
- Cecilia Lindgren,
- Yongmei Liu,
- Tian Liu,
- Youfang Liu,
- Östen Ljunggren,
- Mattias Lorentzon,
- Robert N. Luben,
- William Maixner,
- Fiona E. McGuigan,
- Carolina Medina-Gomez,
- Thomas Meitinger,
- Håkan Melhus,
- Dan Mellström,
- Simon Melov,
- Karl Michaëlsson,
- Braxton D. Mitchell,
- Andrew P. Morris,
- Leif Mosekilde,
- Anne Newman,
- Carrie M. Nielson,
- Jeffrey R. O’Connell,
- Ben A. Oostra,
- Eric S. Orwoll,
- Aarno Palotie,
- Stephen C. J. Parker,
- Munro Peacock,
- Markus Perola,
- Annette Peters,
- Ozren Polasek,
- Richard L. Prince,
- Katri Räikkönen,
- Stuart H. Ralston,
- Samuli Ripatti,
- John A. Robbins,
- Jerome I. Rotter,
- Igor Rudan,
- Veikko Salomaa,
- Suzanne Satterfield,
- Eric E. Schadt,
- Sabine Schipf,
- Laura Scott,
- Joban Sehmi,
- Jian Shen,
- Chan Soo Shin,
- Gunnar Sigurdsson,
- Shad Smith,
- Nicole Soranzo,
- Alena Stančáková,
- Elisabeth Steinhagen-Thiessen,
- Elizabeth A. Streeten,
- Unnur Styrkarsdottir,
- Karin M. A. Swart,
- Sian-Tsung Tan,
- Mark A. Tarnopolsky,
- Patricia Thompson,
- Cynthia A. Thomson,
- Unnur Thorsteinsdottir,
- Emmi Tikkanen,
- Gregory J. Tranah,
- Jaakko Tuomilehto,
- Natasja M. van Schoor,
- Arjun Verma,
- Peter Vollenweider,
- Henry Völzke,
- Jean Wactawski-Wende,
- Mark Walker,
- Michael N. Weedon,
- Ryan Welch,
- H.-Erich Wichmann,
- Elisabeth Widen,
- Frances M. K. Williams,
- James F. Wilson,
- Nicole C. Wright,
- Weijia Xie,
- Lei Yu,
- Yanhua Zhou,
- John C. Chambers,
- Angela Döring,
- Cornelia M. van Duijn,
- Michael J. Econs,
- Vilmundur Gudnason,
- Jaspal S. Kooner,
- Bruce M. Psaty,
- Timothy D. Spector,
- Kari Stefansson,
- Fernando Rivadeneira,
- André G. Uitterlinden,
- Nicholas J. Wareham,
- Vicky Ossowski,
- Dawn Waterworth,
- Ruth J. F. Loos,
- David Karasik,
- Tamara B. Harris,
- Claes Ohlsson,
- Douglas P. Kiel
Affiliations
- M. Carola Zillikens
- Department of Internal Medicine, Erasmus MC
- Serkalem Demissie
- Department of Biostatistics, Boston University School of Public Health
- Yi-Hsiang Hsu
- Hebrew SeniorLife, Institute for Aging Research
- Laura M. Yerges-Armstrong
- Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine
- Wen-Chi Chou
- Hebrew SeniorLife, Institute for Aging Research
- Lisette Stolk
- Department of Internal Medicine, Erasmus MC
- Gregory Livshits
- Sackler Faculty of Medicine, Department of Anatomy and Anthropology, Tel Aviv University
- Linda Broer
- Department of Epidemiology, Erasmus MC
- Toby Johnson
- Department of Medical Genetics, University of Lausanne
- Daniel L. Koller
- Department of Medical and Molecular Genetics, Indiana University School of Medicine
- Zoltán Kutalik
- Department of Medical Genetics, University of Lausanne
- Jian’an Luan
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus
- Ida Malkin
- Sackler Faculty of Medicine, Department of Anatomy and Anthropology, Tel Aviv University
- Janina S. Ried
- Institute of Epidemiology II, Helmholtz Zentrum München – German Research Center for Environmental Health
- Albert V. Smith
- Icelandic Heart Association
- Gudmar Thorleifsson
- deCODE Genetics
- Liesbeth Vandenput
- Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg
- Jing Hua Zhao
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus
- Weihua Zhang
- Department Epidemiology and Biostatistics, School of Public Health, Imperial College
- Ali Aghdassi
- Department of Medicine A, University of Greifswald
- Kristina Åkesson
- Department of Clinical Sciences, Lund University
- Najaf Amin
- Department of Epidemiology, Erasmus MC
- Leslie J. Baier
- Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH
- Inês Barroso
- Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus
- David A. Bennett
- Rush Alzheimer’s Disease Center, Rush University Medical Center
- Lars Bertram
- Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Experimental & Integrative Genomics, University of Lübeck
- Rainer Biffar
- Centre of Oral Health, Department of Prosthetic Dentistry, Gerodontology and Biomaterials, University of Greifswald
- Murielle Bochud
- Centre Hospitalier Universitaire (CHUV), University Institute for Social and Preventive Medicine
- Michael Boehnke
- Department of Biostatistics and Center for Statistical Genetics, University of Michigan
- Ingrid B. Borecki
- Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine
- Aron S. Buchman
- Rush Alzheimer’s Disease Center, Rush University Medical Center
- Liisa Byberg
- Department of Surgical Sciences, Uppsala University
- Harry Campbell
- Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
- Natalia Campos Obanda
- Department of Internal Medicine, Erasmus MC
- Jane A. Cauley
- Department of Epidemiology Graduate School of Public Health, University of Pittsburgh
- Peggy M. Cawthon
- California Pacific Medical Center Research Institute
- Henna Cederberg
- Department of Medicine, University of Eastern Finland and Kuopio University Hospital
- Zhao Chen
- Mel and Enid Zuckerman College of Public Health, University of Arizona
- Nam H. Cho
- Department of Preventive Medicine, Ajou University School of Medicine
- Hyung Jin Choi
- Department of Internal Medicine, Seoul National University College of Medicine
- Melina Claussnitzer
- Hebrew SeniorLife, Institute for Aging Research
- Francis Collins
- Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute
- Steven R. Cummings
- California Pacific Medical Center Research Institute
- Philip L. De Jager
- Harvard Medical School
- Ilja Demuth
- Lipid Clinic at the Interdisciplinary Metabolism Center, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health
- Rosalie A. M. Dhonukshe-Rutten
- Department of Human Nutrition, Wageningen University, PO Box 17
- Luda Diatchenko
- Alan Edwards Centre for Research on Pain, McGill University
- Gudny Eiriksdottir
- Icelandic Heart Association
- Anke W. Enneman
- Department of Internal Medicine, Erasmus MC
- Mike Erdos
- Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute
- Johan G. Eriksson
- Department of General Practice and Primary Health Care, University of Helsinki
- Joel Eriksson
- Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg
- Karol Estrada
- Department of Internal Medicine, Erasmus MC
- Daniel S. Evans
- California Pacific Medical Center Research Institute
- Mary F. Feitosa
- Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine
- Mao Fu
- Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine
- Melissa Garcia
- Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging
- Christian Gieger
- Institute of Epidemiology II, Helmholtz Zentrum München – German Research Center for Environmental Health
- Thomas Girke
- Institute for Integrative Genome Biology, University of California
- Nicole L. Glazer
- Departments of Medicine and Epidemiology, Boston University School of Medicine and Public Health
- Harald Grallert
- Institute of Epidemiology II, Helmholtz Zentrum München – German Research Center for Environmental Health
- Jagvir Grewal
- Cardiology Department, Ealing Hospital NHS Trust
- Bok-Ghee Han
- Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex
- Robert L. Hanson
- Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH
- Caroline Hayward
- MRC Human Genetics Unit, IGMM, University of Edinburgh
- Albert Hofman
- Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)
- Eric P. Hoffman
- Department of Pharmaceutical Sciences, SUNY Binghamton
- Georg Homuth
- Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald
- Wen-Chi Hsueh
- Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH
- Monica J. Hubal
- Department of Exercise and Nutrition Sciences, George Washington University
- Alan Hubbard
- Division of Biostatistics, School of Public Health, University of California
- Kim M. Huffman
- Division of Rheumatology, Department of Medicine, Duke Molecular Physiology Institute, Duke University School of Medicine
- Lise B. Husted
- Endocrinology and Internal Medicine, Aarhus University Hospital
- Thomas Illig
- Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health
- Erik Ingelsson
- Department of Medical Sciences, Uppsala University
- Till Ittermann
- Institute for Community Medicine, University of Greifswald
- John-Olov Jansson
- Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg
- Joanne M. Jordan
- Thurston Arthritis Research Center, University of North Carolina at Chapel Hill
- Antti Jula
- National Institute for Health and Welfare
- Magnus Karlsson
- Department of Clinical Sciences and Orthopaedics, Lund University, Skåne University Hospital SUS
- Kay-Tee Khaw
- Department of Public Health and Primary Care, University of Cambridge
- Tuomas O. Kilpeläinen
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus
- Norman Klopp
- Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health
- Jacqueline S. L. Kloth
- Department of Internal Medicine, Erasmus MC
- Heikki A. Koistinen
- Department of Medicine, University of Helsinki and Helsinki University Central Hospital
- William E. Kraus
- Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute, Duke University School of Medicine
- Stephen Kritchevsky
- Sticht Center on Aging, Wake Forest School of Medicine
- Teemu Kuulasmaa
- Department of Medicine, University of Eastern Finland and Kuopio University Hospital
- Johanna Kuusisto
- Department of Medicine, University of Eastern Finland and Kuopio University Hospital
- Markku Laakso
- Department of Medicine, University of Eastern Finland and Kuopio University Hospital
- Jari Lahti
- Institute of Behavioural Sciences, University of Helsinki
- Thomas Lang
- University of California San Francisco
- Bente L. Langdahl
- Endocrinology and Internal Medicine, Aarhus University Hospital
- Lenore J. Launer
- Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging
- Jong-Young Lee
- Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex
- Markus M. Lerch
- Department of Medicine A, University of Greifswald
- Joshua R. Lewis
- School of Medicine and Pharmacology, University of Western Australia
- Lars Lind
- Department of Medical Sciences, Uppsala University
- Cecilia Lindgren
- Wellcome Trust Centre for Human Genetics, Oxford University
- Yongmei Liu
- Department of Epidemiology and Prevention, Wake Forest School of Medicine
- Tian Liu
- Max Planck Institute for Molecular Genetics
- Youfang Liu
- Thurston Arthritis Research Center, University of North Carolina at Chapel Hill
- Östen Ljunggren
- Department of Medical Sciences, Uppsala University
- Mattias Lorentzon
- Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg
- Robert N. Luben
- Department of Public Health and Primary Care, University of Cambridge
- William Maixner
- Regional Center for Neurosensory Disorders, School of Dentistry, University of North Carolina at Chapel Hill
- Fiona E. McGuigan
- Department of Clinical Sciences, Lund University
- Carolina Medina-Gomez
- Department of Internal Medicine, Erasmus MC
- Thomas Meitinger
- Institute of Human Genetics, MRI, Technische Universität München
- Håkan Melhus
- Department of Medical Sciences, Uppsala University
- Dan Mellström
- Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg
- Simon Melov
- Buck Institute for Research on Aging
- Karl Michaëlsson
- Department of Surgical Sciences, Uppsala University
- Braxton D. Mitchell
- Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine
- Andrew P. Morris
- Wellcome Trust Centre for Human Genetics, Oxford University
- Leif Mosekilde
- Endocrinology and Internal Medicine, Aarhus University Hospital
- Anne Newman
- Center for Aging and Population Health, University of Pittsburgh
- Carrie M. Nielson
- Oregon Health & Science University
- Jeffrey R. O’Connell
- Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine
- Ben A. Oostra
- Department of Clinical Genetics, Erasmus MC
- Eric S. Orwoll
- Oregon Health & Science University
- Aarno Palotie
- Institute for Molecular Medicine Finland (FIMM), University of Helsinki
- Stephen C. J. Parker
- Human Genetics and Computational Medicine and Bioinformatics, University of Michigan
- Munro Peacock
- Department of Medicine, Indiana University School of Medicine
- Markus Perola
- National Institute for Health and Welfare
- Annette Peters
- Institute of Epidemiology II, Helmholtz Zentrum München – German Research Center for Environmental Health
- Ozren Polasek
- Faculty of Medicine, Department of Public Health, University of Split
- Richard L. Prince
- School of Medicine and Pharmacology, University of Western Australia
- Katri Räikkönen
- Institute of Behavioural Sciences, University of Helsinki
- Stuart H. Ralston
- Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, Western General Hospital
- Samuli Ripatti
- Institute for Molecular Medicine Finland (FIMM), University of Helsinki
- John A. Robbins
- Department of Medicine, University of California at Davis
- Jerome I. Rotter
- Institute for Translational Genomic and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor UCLA Medical Center
- Igor Rudan
- Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
- Veikko Salomaa
- National Institute for Health and Welfare
- Suzanne Satterfield
- Department of Preventive Medicine, University of Tennessee Health Science Center
- Eric E. Schadt
- Department of Genetics and Genomic Science, Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai
- Sabine Schipf
- Institute for Community Medicine, University of Greifswald
- Laura Scott
- Department of Biostatistics and Center for Statistical Genetics, University of Michigan
- Joban Sehmi
- Cardiology Department, Ealing Hospital NHS Trust
- Jian Shen
- Oregon Health & Science University
- Chan Soo Shin
- Department of Internal Medicine, Seoul National University College of Medicine
- Gunnar Sigurdsson
- Faculty of Medicine, University of Iceland
- Shad Smith
- Center for Translational Pain Medicine, Department of Anesthiology, Duke University Medical Center
- Nicole Soranzo
- Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus
- Alena Stančáková
- Department of Medicine, University of Eastern Finland and Kuopio University Hospital
- Elisabeth Steinhagen-Thiessen
- Lipid Clinic at the Interdisciplinary Metabolism Center, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health
- Elizabeth A. Streeten
- Program in Personalized and Genomic Medicine, and Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine
- Unnur Styrkarsdottir
- deCODE Genetics
- Karin M. A. Swart
- Department of Epidemiology and Biostatistics, and the EMGO Institute, VU University Medical Center
- Sian-Tsung Tan
- Cardiology Department, Ealing Hospital NHS Trust
- Mark A. Tarnopolsky
- Department of Medicine, McMaster University Medical Center
- Patricia Thompson
- Department of Pathology, Stony Brook School of Medicine
- Cynthia A. Thomson
- Mel and Enid Zuckerman College of Public Health, University of Arizona
- Unnur Thorsteinsdottir
- Faculty of Medicine, University of Iceland
- Emmi Tikkanen
- National Institute for Health and Welfare
- Gregory J. Tranah
- California Pacific Medical Center Research Institute
- Jaakko Tuomilehto
- Vasa Central Hospital
- Natasja M. van Schoor
- Department of Epidemiology and Biostatistics, and the EMGO Institute, VU University Medical Center
- Arjun Verma
- Cardiology Department, Ealing Hospital NHS Trust
- Peter Vollenweider
- Department of Medicine and Internal Medicine, Centre Hospitalier Universitaire Vaudois (CHUV)
- Henry Völzke
- Institute for Community Medicine, University of Greifswald
- Jean Wactawski-Wende
- Department of Epidemiology and Environmental Health, University at Buffalo, State University of New York
- Mark Walker
- Institute of Cellular Medicine, Newcastle University
- Michael N. Weedon
- Genetics of Complex Traits, University of Exeter Medical School
- Ryan Welch
- Department of Biostatistics and Center for Statistical Genetics, University of Michigan
- H.-Erich Wichmann
- Institute of Epidemiology II, Helmholtz Zentrum München – German Research Center for Environmental Health
- Elisabeth Widen
- Institute for Molecular Medicine Finland (FIMM), University of Helsinki
- Frances M. K. Williams
- Department of Twin Research and Genetic Epidemiology, King’s College London, St Thomas’ Campus
- James F. Wilson
- Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
- Nicole C. Wright
- Department of Epidemiology, University of Alabama at Birmingham
- Weijia Xie
- Genetics of Complex Traits, University of Exeter Medical School
- Lei Yu
- Rush Alzheimer’s Disease Center, Rush University Medical Center
- Yanhua Zhou
- Department of Biostatistics, Boston University School of Public Health
- John C. Chambers
- Department Epidemiology and Biostatistics, School of Public Health, Imperial College
- Angela Döring
- Institute of Epidemiology II, Helmholtz Zentrum München – German Research Center for Environmental Health
- Cornelia M. van Duijn
- Department of Epidemiology, Erasmus MC
- Michael J. Econs
- Department of Medicine and Department of Medical and Molecular Genetics, Indiana University School of Medicine
- Vilmundur Gudnason
- Icelandic Heart Association
- Jaspal S. Kooner
- Cardiology Department, Ealing Hospital NHS Trust
- Bruce M. Psaty
- Departments of Medicine, Epidemiology, and Health Services, Cardiovascular Health Research Unit, University of Washington
- Timothy D. Spector
- Department of Twin Research and Genetic Epidemiology, King’s College London, St Thomas’ Campus
- Kari Stefansson
- Faculty of Medicine, University of Iceland
- Fernando Rivadeneira
- Department of Internal Medicine, Erasmus MC
- André G. Uitterlinden
- Department of Internal Medicine, Erasmus MC
- Nicholas J. Wareham
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus
- Vicky Ossowski
- Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH
- Dawn Waterworth
- Medical Genetics, GlaxoSmithKline
- Ruth J. F. Loos
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus
- David Karasik
- Hebrew SeniorLife, Institute for Aging Research
- Tamara B. Harris
- Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute for Aging
- Claes Ohlsson
- Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg
- Douglas P. Kiel
- Hebrew SeniorLife, Institute for Aging Research
- DOI
- https://doi.org/10.1038/s41467-017-00031-7
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 13
Abstract
Lean body mass is a highly heritable trait and is associated with various health conditions. Here, Kiel and colleagues perform a meta-analysis of genome-wide association studies for whole body lean body mass and find five novel genetic loci to be significantly associated.