Exosomes and SARS-CoV-2 infection

Liuying Li; Liuying Li; Zixuan Yang; Jia Li

doi:10.3389/fimmu.2024.1467109

Frontiers in Immunology (Nov 2024)

Exosomes and SARS-CoV-2 infection

Liuying Li,
Liuying Li,
Zixuan Yang,
Jia Li

Affiliations

Liuying Li: Department of Traditional Chinese Medicine, Zigong First People’s Hospital, Zigong, China
Liuying Li: Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China
Zixuan Yang: College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China
Jia Li: College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China

DOI: https://doi.org/10.3389/fimmu.2024.1467109
Journal volume & issue: Vol. 15

Abstract

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Exosomes, which are small extracellular vesicles, are of particular interest in studies on SARS-CoV-2 infection because of their crucial role in intercellular communication. These vesicles are released by several cell types and are rich in “cargo” such as proteins, lipids, and nucleic acids, which are vital for regulating immune response and viral pathogenesis. Exosomes have been reported to be involved in viral transmission, immune escape mechanisms, and illness development in SARS-CoV-2 infection. This review examines the current research on the contribution of exosomes to the interplay between the virus and host cells, highlighting their potential as diagnostic biomarkers and therapeutic targets in combating COVID-19.

Published in Frontiers in Immunology

ISSN: 1664-3224 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: http://journal.frontiersin.org/journal/immunology

About the journal

Abstract

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