Familial segregation of group B streptococcal infection in a consanguineous kindred

Abstract

Two cases of neonatal group B streptococcal (GBS) infection occurring in a large consanguineous kindred are described. The observation suggests that susceptibility to isolated GBS disease in this family may have been the result of an inborn error of immunity inherited as a Mendelian autosomal recessive trait.

Keywords

• Streptococcus agalactiae
• GBS
• Neonatal
• Genetic
• Primary immunodeficiency
• Mendelian